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However, 0165 olanzapine 7.5mg this regimen has yet to be tested in a developing country. In another embodiment, the present invention is directed toward a modified TetR(B) protein comprising a plurality of amino acid substitutions at positions selected from the group consisting of positions 59, 70, 71, 91, 95, 96, 98, 99, 100, 101, 103, 110, 114, 127, 157, 158, 159, 160, 178, 188, 192, 194, 196, 200, and 205 of the TetR(B) protein as depicted in SEQ ID NO: 36, wherein said modified TetR(B) protein binds a TetR(B) operator sequence with greater affinity in the presence of tetracycline than in the absence of tetracycline. Forskolin up-regulates aromatase (CYP19) activity and gene transcripts in the human adrenocortical carcinoma cell line H295R.

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